Potassium Carbonate → HCID 21254039, compound

Participants

Reaction Steps

Using 5.2 g (14 mmol) of 2,4-dichloro-5-(5-difluoromethoxy-4-fluoro-1-methyl-1H-pyrazol-3-yl)benzoyl chloride, 19.2 g (0.14 mol) of potassium carbonate and 9.2 g (28 mmol) of a 25% strength aqueous methoxyamine hydrochloride solution and following the procedure described for Precursor 1.2, a crude product was obtained whose purification by means of silica gel chromatography (eluent:hexane/ethyl acetate=4:1) gave 1.5 g of the desired product of value.

Provenance & Evidence