Hydrochloric Acid → HCID 21249820, compound

HRID 1531645Notes

Reaction equation

HRID 1531645 reaction equation
C[O:2][C:3](=[O:23])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH3:11])=[C:6]([O:12][C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([F:22])([F:21])[F:20])[CH:14]=2)[N:5]=1.[OH-].[Na+].Cl>C(O)C>[CH3:11][O:10][C:7]1[CH:8]=[CH:9][C:4]([C:3]([OH:23])=[O:2])=[N:5][C:6]=1[O:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([C:19]([F:21])([F:22])[F:20])[CH:14]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 54197205HCID 54197205, compound

Product 1

HCID 21249820HCID 21249820, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
70 °C

Procedure

5-methoxy-6-[3-(trifluoromethyl)phenoxy] picolinic acid methyl ester (0.7 g, 0.0021 mol) was dissolved in 2.8 ml of ethyl alcohol. One milliliter of an aqueous solution of sodium hydroxide (0.102 g, 0.0021×1.2 mol) was added to the obtained solution. The resultant mixture was heated and stirred at 70° C. for 1.5 hours. After cooling, the obtained reaction solution was mixed with 2 ml of concentrated hydrochloric acid, thereby precipitating solids. The precipitated solids were filtered out from the solution, washed with water, and then dried.

Workup

  1. temperatureAfter cooling
  2. customthe obtained reaction solution
  3. customprecipitating solids
  4. filtrationThe precipitated solids were filtered out from the solution
  5. washwashed with water
  6. customdried

Sources & evidence

ORD record
ord-d1ef67fe4a3640f7a16ed9a94506f483
Source dataset
uspto-grants-2001_03
Patent number
US06200933B1

Reaction notes

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