Methylamine → HCID 21250420, compound

HRID 1531738Notes

Reaction equation

HRID 1531738 reaction equation
[O:1]=[C:2]1[CH2:7][CH2:6][CH2:5][CH2:4][N:3]1[C:8]1[CH:13]=[CH:12][C:11](F)=[C:10]([N+:15]([O-:17])=[O:16])[CH:9]=1.[CH3:18][NH2:19]>O>[O:1]=[C:2]1[CH2:7][CH2:6][CH2:5][CH2:4][N:3]1[C:8]1[CH:13]=[CH:12][C:11]([NH:19][CH3:18])=[C:10]([N+:15]([O-:17])=[O:16])[CH:9]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 21250345HCID 21250345, compound

Product 1

HCID 21250420HCID 21250420, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4.1 g (0.017 mol) of 4-(2-oxo-piperidin-1-yl)-2-nitro-fluoro-benzene are stirred in 50 ml methylamine solution (40% in H2O) in a sealed vessel for 1 hour at ambient temperature. Then the mixture is diluted with water, suction filtered and dried.

Workup

  1. filtrationfiltered
  2. customdried

Sources & evidence

ORD record
ord-1c79f65c6e8d4cd9a3baac4671942921
Source dataset
uspto-grants-2001_03
Patent number
US06200976B1

Reaction notes

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