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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1531749Generated: October 29, 2026

Phosphorus oxychloride → 2-Chloro-4-methylquinazoline

https://huagongshe.com/reaction/1531749

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 178433509HCID 178433509—
SolventHydrochloric AcidHCID 313—
Product2-Chloro-4-methylquinazolineHCID 15269580—

Reaction Steps

Prepared analogously to Example 27c from 4-methyl-1H-quinazolin-2-one and phosphorus oxychloride in hydrochloric acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06200976B1
Source datasetuspto-grants-2001_03
ORD IDord-d39b378130fb47bb8622abeca03fe552
Source noteuspto-grants-2001_03