4-Aminobenzonitrile → HCID 21250519, compound

HRID 1531750Notes

Reaction equation

HRID 1531750 reaction equation
Cl[C:2]1[N:11]=[C:10]([CH3:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[NH2:13][C:14]1[CH:21]=[CH:20][C:17]([C:18]#[N:19])=[CH:16][CH:15]=1>C(O)(=O)C>[CH3:12][C:10]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=[C:2]([NH:13][C:14]2[CH:21]=[CH:20][C:17]([C:18]#[N:19])=[CH:16][CH:15]=2)[N:11]=1

Participants

4

Reactant 2

HCID 133964-AminobenzonitrileHCID 152695802-Chloro-4-methylquinazoline

Product 1

HCID 21250519HCID 21250519, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Prepared analogously to Example 30a from 2-chloro-4-methyl-quinazoline and 4-aminobenzonitrile in glacial acetic acid.

Sources & evidence

ORD record
ord-5ab9ec63fb93485d9261d78091cb968b
Source dataset
uspto-grants-2001_03
Patent number
US06200976B1

Reaction notes

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