Methanol → HCID 21250315, compound

HRID 1531752Notes

Reaction equation

HRID 1531752 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]([CH3:12])[C:7](=O)[C:6](Cl)=[N:5]2.[NH2:15][C:16]1[CH:23]=[CH:22][C:19]([C:20]#[N:21])=[CH:18][CH:17]=1.C[OH:25]>>[Br:1][C:2]1[CH:3]=[C:4]2[C:9]([N:8]([CH3:12])[CH:7]([NH:15][C:16]3[CH:23]=[CH:22][C:19]([C:20]#[N:21])=[CH:18][CH:17]=3)[C:6](=[O:25])[NH:5]2)=[CH:10][CH:11]=1

Participants

4

Reactant 3

HCID 887Methanol2×HCID 133964-AminobenzonitrileHCID 21250521HCID 21250521, compound

Product 1

HCID 21250315HCID 21250315, compound

Conditions

Temperature
40 °C

Procedure

270 mg (1 mmol) of 6-bromo-3-chloro-1-methyl-1H-quinoxalin-2-one and 240 mg (2 mmol) of 4-aminobenzonitrile are heated to 100° C. in 3 ml methanol. The precipitate is cooled to 40° C., diluted with methanol and suction filtered.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-d0bc1515a9d94a7791a5dd651d5f9e43
Source dataset
uspto-grants-2001_03
Patent number
US06200976B1

Reaction notes

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