HCID 18361764, compound → HCID 18361839, compound

Participants

Reaction Steps

The title-compound was prepared from 6-chloro-3-(isoxazol-3-yl)-1,2,4-triazolo[3,4-a]phthalazine (described in Example 34 part b) and 2-propyl-3-hydroxymethyl-1,2,4-triazole prepared as described in WO-A-9804559 using the procedure given for Example 71, 1H NMR (360 MHz, CDCl3) δ 0.95 (3H, t, J=7.4 Hz, Ar—H), 1.91-2.01 (2H, m, CH2), 4.34 (2H, t, J=7.0 Hz, CH2), 5.85 (2H, s, CH2), 7.28 (1H, d, J=1.7 Hz, Ar—H), 7.83 (1H, t, J=8.3 Hz, Ar—H), 7.96-8.01 (2H, m, 2 of Ar—H), 8.21 (1H, d, J=7.9 Hz, Ar—H), 8.62 (1H, s, Ar—H), 8.70 (1H, d, J=7.1 Hz, Ar—H); MS (ES30) m/e 377 [MH]+; Anal. Found. C, 57.12; H, 3.87; N, 29.49. C18H16N8O2.0.05CH2Cl2 requires C, 56.96; H, 4.26; N. 29.44%.

Provenance & Evidence