HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → 3-Bromomethyl-5-[phenoxymethyl]benzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | 3,5-Bis(bromomethyl)benzoic acid ethyl ester | HCID 15440343 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Bromomethyl-5-[phenoxymethyl]benzoic acid ethyl ester | HCID 70222550 | — |
Reaction Steps
The subtitle compound was prepared from 3,5-bis[bromomethyl]benzoic acid ethyl ester (5.18 g) and phenol (1.45 g) in dimethylformamide (10 ml) by the method of example 7 step (i). Yield after chromatography, eluting with 10% ethyl acetate in isohexane, 2.13 g of a mixture containing 15% product and 85% diphenoxy compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06200981B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-e9f538f7eebc4f93b1e359966dd15f2a |
| Source note | uspto-grants-2001_03 |