Sulfuric Acid → HCID 60166995, compound

HRID 1531929Notes

Reaction equation

HRID 1531929 reaction equation
[OH:1][C:2]1[CH:11]=[CH:10][C:9]([CH3:12])=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5].S(=O)(=O)(O)O.[C:18](OC(=O)C)(=[O:20])[CH3:19]>>[C:18]([O:1][C:2]1[CH:11]=[CH:10][C:9]([CH3:12])=[CH:8][C:3]=1[C:4]([O:6][CH3:7])=[O:5])(=[O:20])[CH3:19]

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 7918Acetic AnhydrideHCID 89802Methyl 5-methylsalicylate

Product 1

HCID 60166995HCID 60166995, compound

Procedure

A solution of the product from step (i) (5.87 g) in acetic anhydride (4.32 g) was treated with concentrated sulphuric acid (0.5 ml) and stirred for 72 hours. The mixture was poured into ice-water and extracted with diethyl ether. The extract was washed with water and saturated aqueous sodium bicarbonate, dried (MgSO4) and evaporated. Yield 5.5 g.

Workup

  1. extractionextracted with diethyl ether
  2. washThe extract was washed with water and saturated aqueous sodium bicarbonate
  3. dry with materialdried (MgSO4)
  4. customevaporated

Sources & evidence

ORD record
ord-988617784eb243b1834b4aec1bd4c4a5
Source dataset
uspto-grants-2001_03
Patent number
US06200981B1

Reaction notes

Loading…