Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 131722446 | HCID 131722446 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 21250887 | HCID 21250887 | — |
Reaction Steps
A mixture of the product from step (vi) (0.073 g) and sodium hydroxide (1 g) in methanol (20 ml) and water (20 ml) was heated at 60° C. overnight. The mixture was acidified with 2M HCl and extracted with ethyl acetate. The extract was evaporated and the residue purified by reverse phase chromatography. Yield 0.04 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06200981B1 |
|---|
| Source dataset | uspto-grants-2001_03 |
|---|
| ORD ID | ord-7a07e72950b34282b47c96599545559f |
|---|
| Source note | uspto-grants-2001_03 |
|---|
