Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 131722449 | HCID 131722449 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 131722448 | HCID 131722448 | — |
Reaction Steps
A mixture of the product from example 2 step (iv) (1 g), sodium bicarbonate (0.22 g) and methyl iodide (0.7 ml) in water (4 ml) and methanol (30 ml) was heated at 40° C. for 4 hours. The mixture was concentrated under reduced pressure and partitioned between ethyl acetate and water. The organic phase was dried (MgSO4) and evaporated. Used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06200981B1 |
|---|
| Source dataset | uspto-grants-2001_03 |
|---|
| ORD ID | ord-61974cfada374bcab5acb27437ff9bc5 |
|---|
| Source note | uspto-grants-2001_03 |
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