反应详情

To a stirred solution of 5-(4-nitrophenoxy)-3-chloropyridine (219 mg, 0.873 mmol) in EtOH (4 mL) was added SnCl2 (730 mg, 3.24 mmol). The solution was refluxed for 1.25 hr and the solvent was removed by evaporation. The resulting crude solid was purified by chromatography (97.5:2.5 CH2Cl2:MeOH) to provide 187.7 mg (78% yield) of the title compound.

1. temperatureThe solution was refluxed for 1.25 hr
2. customthe solvent was removed by evaporation
3. customThe resulting crude solid was purified by chromatography (97.5:2.5 CH2Cl2:MeOH)