HCID 22459046, compound → HCID 22458983, compound

HRID 1532165Notes

Reaction equation

HRID 1532165 reaction equation
[C:1]1([CH2:7][CH2:8][C:9]2[C:13]3[CH:14]=[CH:15][C:16]([OH:21])=[C:17]([CH2:18][CH:19]=[CH2:20])[C:12]=3[S:11][CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(OC)(C)(C)C.[Pd]>[C:1]1([CH2:7][CH2:8][C:9]2[C:13]3[CH:14]=[CH:15][C:16]([OH:21])=[C:17]([CH2:18][CH2:19][CH3:20])[C:12]=3[S:11][CH:10]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 1

HCID 22459046HCID 22459046, compound

Product 1

HCID 22458983HCID 22458983, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 15413tert-Butyl methyl etherSolvent

Procedure

The product from Step G (3.062 grams) was dissolved in methyl tert-butyl ether (60 mL) and placed in a hydrogenation bottle. 5% Pd/C catalyst (306 mg) was added and the mixture hydrogenated for 1 hour using a Parr apparatus (14 psi). Filtration through Celite and evaporation gave the title compound as a yellow oil. On standing, a pale yellow solid was produced which required no additional purification.

Workup

  1. filtrationFiltration
  2. customthrough Celite and evaporation

Sources & evidence

ORD record
ord-040f4d3b6c704324b692fbef6fa0b5a5
Source dataset
uspto-grants-2001_03
Patent number
US06200998B1

Reaction notes

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