HCID 15518370, compound → HCID 22013785, compound

HRID 1532646Notes

Reaction equation

HRID 1532646 reaction equation
[ClH:1].C(OCC)(=O)C.[CH2:8]([C:29]1[N:33]([CH2:34][CH2:35][CH2:36][N:37]([CH3:39])[CH3:38])[C:32]2[CH:40]=[CH:41][CH:42]=[CH:43][C:31]=2[N:30]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>C(OCC)(=O)C>[ClH:1].[CH2:8]([C:29]1[N:33]([CH2:34][CH2:35][CH2:36][N:37]([CH3:38])[CH3:39])[C:32]2[CH:40]=[CH:41][CH:42]=[CH:43][C:31]=2[N:30]=1)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

Participants

4

Reactant 2

HCID 15518370HCID 15518370, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 22013785HCID 22013785, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

4N Hydrochloric acid/ethyl acetate solution (0.11 ml) was added to a solution containing 3-(2-henicosyl-1H-benzimidazol-1-yl)-N,N-dimethyl-1-propanamine (0.20 g) in ethyl acetate (2 ml). After being stirred for 20 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethanol-ethyl acetate, thereby yielding the entitled compound (0.19 g) as white solid.

Workup

  1. concentrationthe reaction mixture was concentrated
  2. customThe residue was recrystallized with the mixed solution of ethanol-ethyl acetate

Sources & evidence

ORD record
ord-91669861cc894b55a7fdec9684bdd122
Source dataset
uspto-grants-2001_03
Patent number
US06204264B1

Reaction notes

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