HCID 15869139, compound → 262357-39-1

HRID 1532649Notes

Reaction equation

HRID 1532649 reaction equation
[N:1]1([CH2:6][CH2:7][CH2:8][NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[N+:16]([O-])=O)[CH:5]=[CH:4][N:3]=[CH:2]1>C(O)C.[C].[Pd]>[N:1]1([CH2:6][CH2:7][CH2:8][NH:9][C:10]2[C:11]([NH2:16])=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

4

Reactant 1

HCID 15869139HCID 15869139, compound

Product 1

HCID 22013745262357-39-1Yield 99.7%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

10% of palladium-carbon (0.804 g) was added to a solution containing N-[3-(1H-imidazol-1-yl)propyl]-2-nitroaniline (4.000 g) in ethanol (40 ml) and stirred for 4.5 hours under a hydrogen gas atmosphere at room temperature. After the catalyst was removed out by filtration, the filtrate was concentrated, thereby yielding the entitled compound (3.503 g) as black solid.

Workup

  1. customAfter the catalyst was removed out by filtration
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-80b278526eed4dfeba799c623ef56170
Source dataset
uspto-grants-2001_03
Patent number
US06204264B1

Reaction notes

Loading…