HCID 3635836, compound → HCID 22013772, compound

HRID 1532652Notes

Reaction equation

HRID 1532652 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([CH2:7][CH2:8][CH2:9][NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[N+:17]([O-])=O)[CH2:3][CH2:2]1>C(O)C.[C].[Pd]>[O:1]1[CH2:2][CH2:3][N:4]([CH2:7][CH2:8][CH2:9][NH:10][C:11]2[C:12]([NH2:17])=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH2:5][CH2:6]1

Participants

4

Reactant 1

HCID 3635836HCID 3635836, compound

Product 1

HCID 22013772HCID 22013772, compoundYield 72.3%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

10% of palladium-carbon (0.237 g) was added to a solution containing N-(3-morpholinopropyl)-2-nitroaniline (1.040 g) in ethanol (12 ml) and the mixture was stirred for 7 hours under a hydrogen gas atmosphere at room temperature. After the catalyst was removed out by filtration, the filtrate was concentrated, thereby yielding the entitled compound (0.667 g) as blackish brown solid.

Workup

  1. customAfter the catalyst was removed out by filtration
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-1a6fd057d8774fbebee166422eacf186
Source dataset
uspto-grants-2001_03
Patent number
US06204264B1

Reaction notes

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