HCID 22013755, compound → HCID 22013764, compound

HRID 1532668Notes

Reaction equation

HRID 1532668 reaction equation
[CH3:1][N:2]([CH3:21])[CH2:3][CH2:4][CH2:5][NH:6][C:7]1[CH:17]=[CH:16][C:10]([C:11]([N:13]([CH3:15])[CH3:14])=[O:12])=[CH:9][C:8]=1[N+:18]([O-])=O>C(O)C.[C].[Pd]>[NH2:18][C:8]1[CH:9]=[C:10]([CH:16]=[CH:17][C:7]=1[NH:6][CH2:5][CH2:4][CH2:3][N:2]([CH3:1])[CH3:21])[C:11]([N:13]([CH3:15])[CH3:14])=[O:12]

Participants

4

Reactant 1

HCID 22013755HCID 22013755, compound

Product 1

HCID 22013764HCID 22013764, compoundYield 102.3%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

10% of palladium-carbon (0.56 g) was added to a solution containing 4-{[3-(dimethylamino)propyl]amino}-N,N-dimethyl-3-nitrobenzamide (2.82 g) in ethanol (20 ml) and the mixture was stirred for 13 hours under a hydrogen gas atmosphere at room temperature. After the catalyst was removed out by filtration, the filtrate was concentrated, thereby yielding the entitled compound (2.59 g) as dark red solid.

Workup

  1. customAfter the catalyst was removed out by filtration
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-77bacec6fc0045a8a6f9f93863987be3
Source dataset
uspto-grants-2001_03
Patent number
US06204264B1

Reaction notes

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