反应详情

4N Hydrochloric acid/ethyl acetate solution (1.44 ml) was added to a solutior containing 2-(2-henicosyl-1H-benzimidazol-1-yl)-N,N-dimethyl-1-ethanamine (2.580 g) in ethyl acetate (26 ml). After being stirred for 30 minutes at room temperature, the reaction mixture was concentrated. The residue was recrystallized with the mixed solution of ethyl acetate-ethanol, thereby yielding the entitled compound (2.269 g) as white crystals.

1. concentrationthe reaction mixture was concentrated
2. customThe residue was recrystallized with the mixed solution of ethyl acetate-ethanol