HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-{[(4-Chlorophenyl)methyl]amino}propan-1-ol → HCID 11150002, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-{[(4-Chlorophenyl)methyl]amino}propan-1-ol | HCID 3382599 | — |
| Reactant | 4-Benzyl-2-(chloromethyl)-1,4-oxazepane | HCID 10399365 | — |
| Product | HCID 11150002 | HCID 11150002 | 29% |
Reaction Steps
(±)-4-(4-Chlorobenzyl)-2-(chloromethyl)perhydro-1,4-oxazepin was prepared analogously to the method for the preparation of (±)-4-benzyl-2-(chloro-methyl)perhydro-1,4-oxazepin described in K. Araki et al. J. Med. Chem. 36, 1356 (1993), using N-(4-Chlorobenzyl)-N-(3-hydroxypropyl)amine as starting material. Yield 29%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06207662B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-166e027e82484b3bb22248ad1cce6d3f |
| Source note | uspto-grants-2001_03 |