HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Viloxazine Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 47374-79-8 | HCID 12297772 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Viloxazine Hydrochloride | HCID 71424 | 96% |
Reaction Steps
The title compound was prepared by hydrogenation of (±)-4-benzyl-2-[(2-ethoxyphenoxy)-methyl]morpholine over 5% Pd/C in ethanol: 1 M aqueous HCl 3:1. mp 176-179° C. Yield 96%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06207662B1 |
| Source dataset | uspto-grants-2001_03 |
| ORD ID | ord-61fa7fb9104b4d309a32f21e50739f69 |
| Source note | uspto-grants-2001_03 |