Methyl 3-(2-hydroxyphenyl)prop-2-enoate → Methyl 3-(2-hydroxyphenyl)propionate

HRID 1533247Notes

Reaction equation

HRID 1533247 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH:8]=[CH:9][C:10]([O:12][CH3:13])=[O:11]>[Pd].CO>[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][C:10]([O:12][CH3:13])=[O:11]

Participants

4

Reactant 1

HCID 89400Methyl 3-(2-hydroxyphenyl)prop-2-enoate

Product 1

HCID 2794569Methyl 3-(2-hydroxyphenyl)propionateYield 100.1%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of methyl 3-(2-hydroxyphenyl)acrylate (2.47 g) and 10% palladium on carbon (0.50 g) in methanol (30 ml) was stirred under hydrogen atmosphere for 3 hours. The mixture was filtered and the filtrate was evaporated under reduced pressure to afford methyl 3-(2-hydroxyphenyl)propionate (2.50 g).

Workup

  1. filtrationThe mixture was filtered
  2. customthe filtrate was evaporated under reduced pressure

Sources & evidence

ORD record
ord-c4df573437c7492cb725e0551538753d
Source dataset
uspto-grants-2001_03
Patent number
US06207686B1

Reaction notes

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