反应详情

Methyl 3-(2-methoxyphenyl)propionate (1.80 g) was reacted with cyclohexane carbaldehyde (1.25 g) in substantially the same manner as that of Preparation 1-4) to give less polar isomer of methyl (2RS,3SR)-3-cyclohexyl-3-hydroxy-2-(2-methoxyphenylmethyl)propionate (isomer A) (0.706 g) and more polar isomer of (2RS,3RS)-isomer of the same (isomer B) (0.940 g).

1. customof Preparation 1-4)