(3-Bromophenyl)acetic acid → 2-[(3-bromophenyl)acetamido]butyric Acid isobutyl Ester

HRID 1533556Notes

Reaction equation

HRID 1533556 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH2:8][C:9]([OH:11])=O)[CH:5]=[CH:6][CH:7]=1.[NH2:12][CH:13]([CH2:21][CH3:22])[C:14]([O:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[O:15]>>[CH2:17]([O:16][C:14](=[O:15])[CH:13]([NH:12][C:9](=[O:11])[CH2:8][C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Br:1])[CH:3]=1)[CH2:21][CH3:22])[CH:18]([CH3:19])[CH3:20]

Participants

3

Reactant 2

HCID 74653(3-Bromophenyl)acetic acidHCID 13743360Isobutyl 2-aminobutyrate

Product 1

HCID 154817712-[(3-bromophenyl)acetamido]butyric Acid isobutyl Ester

Procedure

Following General Procedure I′ above and using 3-bromophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure J′ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-034f90b4489544778431e802780c11a0
Source dataset
uspto-grants-2001_03
Patent number
US06207710B1

Reaction notes

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