Dimethylformamide → (RS)-N-(4-cyano-benzyl)-2-(4-isopropoxy-phenyl)-2-methoxy-acetamide

HRID 153383Notes

Reaction equation

HRID 153383 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:8][C:9]([CH:10]([O:11][CH3:12])[c:13]2[cH:14][cH:15][c:16]([OH:19])[cH:17][cH:18]2)=[O:20])[cH:21][cH:22]1.[C:23](=[O:24])([O-:25])[O-:26].[Cs+:27].[Cs+:32].[I:28][CH:29]([CH3:30])[CH3:31].[O:33]=[CH:34][N:35]([CH3:36])[CH3:37]>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:8][C:9]([CH:10]([O:11][CH3:12])[c:13]2[cH:14][cH:15][c:16]([O:19][CH:29]([CH3:30])[CH3:31])[cH:17][cH:18]2)=[O:20])[cH:21][cH:22]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6362Isopropyl iodideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 21905457(RS)-N-(4-cyano-benzyl)-2-(4-hydroxy-phenyl)-2-methoxy-acetamide

Product 1

HCID 21904885(RS)-N-(4-cyano-benzyl)-2-(4-isopropoxy-phenyl)-2-methoxy-acetamide

Sources & evidence

ORD record
ord-eb56045efa6148b5bc5cdc1c22da46af
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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