Potassium Iodide → HCID 15030076, compound

HRID 1533914Notes

Reaction equation

HRID 1533914 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl[CH2:17][CH2:18][CH:19]1[O:23][C:22](=[O:24])[N:21]([CH3:25])[CH2:20]1.C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+]>C(O)CCC.C(#N)C>[CH3:25][N:21]1[CH2:20][CH:19]([CH2:18][CH2:17][N:13]2[CH2:14][CH2:15][N:10]([C:7]3[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=3)[CH2:11][CH2:12]2)[O:23][C:22]1=[O:24]

Participants

7

Reactant 4

HCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 804471-(4-Nitrophenyl)piperazineHCID 146987465-(2-Chloro-ethyl)-3-methyl-oxazolidin-2-one

Product 1

HCID 15030076HCID 15030076, compoundYield 79.3%

Reagents, catalysts & solvents 2

HCID 2631-ButanolSolventHCID 6342AcetonitrileSolvent

Procedure

This compound was prepared according to the procedure of Example 2. A mixture of 4.1 g (0.02 mol) of 1-(4-nitrophenyl)piperazine, 3.3 g (0.02 mol) of 5-(2-chloroethyl)-3-methyl-2-oxazolidinone, 6.4 g (0.06 mol) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 100 mL of 1-butanol gave 5.3 g (79%) of yellow solid, mp 155°-156° C. (acetonitrile).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-7067e05d5d244dc88bc11fe6bafa5648
Source dataset
uspto-grants-1992_02
Patent number
US05086055

Reaction notes

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