Potassium Iodide → HCID 15030078, compound

HRID 1533916Notes

Reaction equation

HRID 1533916 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1.Cl[CH2:15][CH2:16][CH:17]1[O:21][C:20](=[O:22])[N:19]([CH3:23])[CH2:18]1.C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+]>C(O)CCC.CC(O)C>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][N:11]([CH2:15][CH2:16][CH:17]2[O:21][C:20](=[O:22])[N:19]([CH3:23])[CH2:18]2)[CH2:10][CH2:9]1

Participants

7

Reactant 4

HCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 4156281-(2-Chlorophenyl)piperazineHCID 146987465-(2-Chloro-ethyl)-3-methyl-oxazolidin-2-one

Product 1

HCID 15030078HCID 15030078, compoundYield 75%

Reagents, catalysts & solvents 2

HCID 2631-ButanolSolventHCID 3776IsopropanolSolvent

Procedure

This compound was prepared according to the procedure of Example 2. A mixture of 5.5 g (0.028 mol) of 1-(2-chlorophenyl)piperazine (Aldrich), 4.6 g (0.028 mol) of 5-(2-chloroethyl)-3-methyl-2-oxazolidinone, 8.9 g (0.08 mol) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 150 mL of 1-butanol gave 6.8 g (75%) of off-white solid, mp 79.5°-81.5° C. (2-propanol).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-97b915b234db426eacf507ba60b4a324
Source dataset
uspto-grants-1992_02
Patent number
US05086055

Reaction notes

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