HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 86745447, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | Fumaric Acid | HCID 444972 | — |
| Reactant | 1-(4-Chloro-3-(trifluoromethyl)phenyl)piperazine | HCID 2778137 | — |
| Reactant | 5-(2-Chloro-ethyl)-3-methyl-oxazolidin-2-one | HCID 14698746 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 86745447 | HCID 86745447 | 78% |
Reaction Steps
This compound was prepared according to the procedure of Example 2. A mixture of 4.0 g (0.15 mol) of 1-(4-chloro-3-trifluoromethylphenyl)piperazine (Emka-Chemie), 2.5 g (0.015 mol) of 5-(2-chloroethyl)-3-methyl-2-oxazolidinone, 5.3 g (0.05 mol) of anhydrous sodium carbonate and 0.4 g of potassium iodide in 100 mL of 1-butanol gave a gum as residue. The gum was converted to the fumaric acid salt and the solid was recrystallized from 95% ethanol to yield 5.7 g (78%) of white solid, mp 198°-201° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05086055 |
| Source dataset | uspto-grants-1992_02 |
| ORD ID | ord-49a011ed87944ab0a91c24a061e9e986 |
| Source note | uspto-grants-1992_02 |