Potassium Iodide → HCID 15030087, compound

HRID 1533923Notes

Reaction equation

HRID 1533923 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([N:13]2[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]2)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10].Cl[CH2:20][CH2:21][CH:22]1[O:26][C:25](=[O:27])[N:24]([CH3:28])[CH2:23]1.C(=O)([O-])[O-].[Na+].[Na+].[I-].[K+]>C(O)CCC.CC(O)C>[CH3:28][N:24]1[CH2:23][CH:22]([CH2:21][CH2:20][N:16]2[CH2:17][CH2:18][N:13]([C:5]3[CH:4]=[C:3]([O:2][CH3:1])[C:8]([O:9][CH3:10])=[C:7]([O:11][CH3:12])[CH:6]=3)[CH2:14][CH2:15]2)[O:26][C:25]1=[O:27]

Participants

7

Reactant 4

HCID 4875Potassium IodideHCID 10340Sodium CarbonateHCID 38387651-(3,4,5-Trimethoxyphenyl)piperazineHCID 146987465-(2-Chloro-ethyl)-3-methyl-oxazolidin-2-one

Product 1

HCID 15030087HCID 15030087, compoundYield 42.2%

Reagents, catalysts & solvents 2

HCID 2631-ButanolSolventHCID 3776IsopropanolSolvent

Procedure

This compound was prepared according to the procedure of Example 2. A mixture of 3.8 g (0.015 mol) of 1-(3,4,5-trimethoxyphenyl)piperazine, 2.5 g (0.015 mol) of 5-(2-chloroethyl)-3-methyl-2-oxazolidinone, 5.3 g (0.05 mol) of anhydrous sodium carbonate and 0.3 g of potassium iodide in 100 mL of 1-butanol gave 2.4 g (42%) of white solid, mp 86°-88° C. (2-propanol).

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-7fc68403e09c4b7680688104c5f3b085
Source dataset
uspto-grants-1992_02
Patent number
US05086055

Reaction notes

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