1-Phenylpiperazine → HCID 67918712, compound

HRID 1533931Notes

Reaction equation

HRID 1533931 reaction equation
Cl[CH2:2][CH:3]1[O:7][C:6](=[O:8])[NH:5][CH2:4]1.[C:9]1([N:15]2[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[C:21]([OH:28])(=[O:27])/[CH:22]=[CH:23]\[C:24]([OH:26])=[O:25]>>[C:21]([OH:28])(=[O:27])/[CH:22]=[CH:23]\[C:24]([OH:26])=[O:25].[C:9]1([N:15]2[CH2:20][CH2:19][N:18]([CH2:2][CH:3]3[O:7][C:6](=[O:8])[NH:5][CH2:4]3)[CH2:17][CH2:16]2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

4

Reactant 3

HCID 70961-PhenylpiperazineHCID 908155-Chloromethyloxazolidin-2-oneHCID 444266Maleic Acid

Product 1

HCID 67918712HCID 67918712, compound

Procedure

Following the procedure of Example 35, the free base was prepared from 5-chloromethyl-2-oxazolidinone and 1-phenylpiperazine. The product was converted to the maleic acid salt, mp 166°-168° C.

Sources & evidence

ORD record
ord-9a52bfdfc56d46d0a9b03dcaebf508b6
Source dataset
uspto-grants-1992_02
Patent number
US05086055

Reaction notes

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