Water → HCID 14570909, compound

HRID 1534260Notes

Reaction equation

HRID 1534260 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([CH2:8][CH2:9][CH3:10])[C:5]([OH:11])=[CH:4][C:3]=1[OH:12].[CH2:13]1N2CN3CN(C2)CN1C3.[OH2:23]>FC(F)(F)C(O)=O>[Cl:1][C:2]1[C:3]([OH:12])=[C:4]([C:5]([OH:11])=[C:6]([CH2:8][CH2:9][CH3:10])[CH:7]=1)[CH:13]=[O:23]

Participants

5

Reactant 3

HCID 962WaterHCID 4101HexamethylenetetramineHCID 2381734-chloro-6-propylbenzene-1,3-diol

Product 1

HCID 14570909HCID 14570909, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

To a solution of 2-chloro-4-propyl-1,5-dihydroxybenzene (from Step a, 243 mg, 1.3 mmol) in 10 mL trifluoroacetic acid was added 1 g of hexamine. The mixture was refluxed for 20 h. Water was added and the mixture was extracted with ethyl acetate. Chromatography of the concentrated organic extracts gave the title compound.

Workup

  1. temperatureThe mixture was refluxed for 20 h
  2. extractionthe mixture was extracted with ethyl acetate

Sources & evidence

ORD record
ord-8d39a2b78efa4dd39806b9c82984a1a6
Source dataset
uspto-grants-1992_02
Patent number
US05087638

Reaction notes

Loading…