Isopropanol → 2-Chloro-3,3,4,4-tetrafluorocyclobutenyl isopropyl ether

HRID 1534275Notes

Reaction equation

HRID 1534275 reaction equation
[OH-].[Na+].Cl[C:4]1[C:7]([F:9])([F:8])[C:6]([F:11])([F:10])[C:5]=1[Cl:12].[CH:13]([OH:16])([CH3:15])[CH3:14]>>[CH:13]([O:16][C:4]1[C:7]([F:9])([F:8])[C:6]([F:11])([F:10])[C:5]=1[Cl:12])([CH3:15])[CH3:14]

Participants

4

Reactant 3

HCID 3776IsopropanolHCID 14798Sodium HydroxideHCID 1362201,2-Dichlorotetrafluorocyclobutene-1

Product 1

HCID 199110632-Chloro-3,3,4,4-tetrafluorocyclobutenyl isopropyl ether

Procedure

200 g (5 mol) of powdered sodium hydroxide are metered into a solution of 786 g (3.94 mol) of 1,2-dichloro-3,3,4,4-tetrafluorocyclobutene and 328 g (5.47 mol) of technical grade isopropanol at -10° C. The mixture is stirred for a further 2 hours, the solid is filtered off with suction and the filtrate is distilled.

Workup

  1. filtrationthe solid is filtered off with suction
  2. distillationthe filtrate is distilled

Sources & evidence

ORD record
ord-37905d25793140dda77f06fadc3e3d0c
Source dataset
uspto-grants-1992_02
Patent number
US05087775

Reaction notes

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