HCID 13448027, compound → HCID 53733853, compound

HRID 1534331Notes

Reaction equation

HRID 1534331 reaction equation
C([NH:3][C:4](CC(C)=C)(C(OCC)=O)[C:5]([O:7][CH2:8][CH3:9])=[O:6])=O.[CH:19]([NH:21][CH2:22][C:23]([NH:25][CH:26]([CH2:31][CH:32]=[CH2:33])[C:27]([O:29][CH3:30])=[O:28])=[O:24])=[O:20]>C(Cl)Cl.CO>[NH2:3][CH:4]([C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH2:33][CH:32]=[CH:31][CH:26]([NH:25][C:23](=[O:24])[CH2:22][NH:21][CH:19]=[O:20])[C:27]([O:29][CH3:30])=[O:28]

Participants

4

Reactant 2

HCID 13448027HCID 13448027, compoundHCID 19909486HCID 19909486, compound

Product 1

HCID 53733853HCID 53733853, compound

Reagents, catalysts & solvents 1

HCID 21226129Dichloromethane methanolSolvent

Procedure

Using the procedure of preparation B of Example 1, diethyl (formylamino)-(2-methyl-2-propenyl)-propanedioate in Step 2 was replaced by methyl 2-[(N-formylglycyl)-amino]-2-(2-propenyl)ethanoate to obtain the expected product with an Rf=0.2 in a methylene chloride/methanol (9:1) mixture.

Sources & evidence

ORD record
ord-03d741cfec084fd4b7c31780efbd64d6
Source dataset
uspto-grants-1992_02
Patent number
US05089476

Reaction notes

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