Potassium Carbonate → 1920-12-3

HRID 1534407Notes

Reaction equation

HRID 1534407 reaction equation
[ClH:1].[C:2]1(=[O:16])[N:6]([CH2:7][C:8](=[NH:10])O)[C:5](=[O:11])[C:4]2=[CH:12][CH:13]=[CH:14][CH:15]=[C:3]12.C(=O)([O-])[O-].[K+].[K+].[Cl-].[NH4+:24]>CO>[ClH:1].[C:2]1(=[O:16])[N:6]([CH2:7][C:8]([NH2:24])=[NH:10])[C:5](=[O:11])[C:4]2=[CH:12][CH:13]=[CH:14][CH:15]=[C:3]12

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 25517Ammonium ChlorideHCID 178479559HCID 178479559, compound

Product 1

HCID 200866281920-12-3

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 2-phthalimidoacetimidate hydrochloride (6 g, Chem. Ber., 1964, 97, 528) and a saturated aqueous potassium carbonate solution (50 ml) was stirred at ambient temperature for 3 minutes and then extracted with chloroform. The organic phase was dried (Na2SO4) and evaporated. A mixture of the solid so obtained, ammonium chloride (1.4 g) and methanol (100 ml) was stirred at laboratory temperature for 18 hours. The mixture was evaporated to give 2-phthalimidoacetamidine hydrochloride, as a white solid (5.5 g).

Workup

  1. extractionextracted with chloroform
  2. dry with materialThe organic phase was dried (Na2SO4)
  3. customevaporated
  4. additionA mixture of the solid
  5. customso obtained
  6. customThe mixture was evaporated

Sources & evidence

ORD record
ord-7ee7bc25479d446ead4273799288df48
Source dataset
uspto-grants-1992_02
Patent number
US05089499

Reaction notes

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