HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyano-4-methylpyridine → (4-Methylpyridin-2-yl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyano-4-methylpyridine | HCID 88739 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ammonia | HCID 222 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (4-Methylpyridin-2-yl)methanamine | HCID 15144432 | — |
Reaction Steps
g 2 (0.0169 moles) of 2-cyano-4-methyl pyridine [J. Am. Chem. Soc. 78, 5842-5843 (1956)] dissolved in 400 ml of methanol containing 12% W/W of ammonia, were hydrogenated on 2 g of Ni-Raney at room temperature and 20 psi, until the theoretical amount of hydrogen was consumed.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05089507 |
| Source dataset | uspto-grants-1992_02 |
| ORD ID | ord-90ba9699cfbd43dd8d89473c0b7be1d6 |
| Source note | uspto-grants-1992_02 |