HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-2-(pyrrolidin-1-yl)carbonyl piperidine → HCID 15165786, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-2-(pyrrolidin-1-yl)carbonyl piperidine | HCID 19909692 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15165786 | HCID 15165786 | — |
Reaction Steps
By reducing g 4.5 (0.023 moles) of 5-methyl-2-(pyrrolidin-1-yl)carbonyl piperidine with LiAlH4 in THF the corresponsing diamine was obtained. The diastereoisomeric composition was checked by GLC performed on a 10 m Ph-Me silicone 50% capillary column, from 80° to 180° (rate 5° /min). Diast. A Rt 8.86 (57.93%), Diast. B. Rt 9.11 (42.07%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05089507 |
| Source dataset | uspto-grants-1992_02 |
| ORD ID | ord-70701c24e67844c3950818c767fe4d90 |
| Source note | uspto-grants-1992_02 |