HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 2-Methyl-6-[(pyrrolidin-1-yl)methyl]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | 6-Methyl-2-pyridylmethanol | HCID 70736 | — |
| Product | 2-Methyl-6-[(pyrrolidin-1-yl)methyl]pyridine | HCID 15123265 | — |
Reaction Steps
By reaction of 6-methyl-2-pyridyl methanol [prepared as described in Helv. Chim. Acta, 2429 (1957)], g 7.1 (0.058 moles), with methanesulfonyl chloride and then with pyrrolidine as in Description 1, g 7.5 of yellow oil (b.p. 62°-65° C. 80 mmHg) were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05089507 |
| Source dataset | uspto-grants-1992_02 |
| ORD ID | ord-fbbafb301d894a4f834c540c6e0fd507 |
| Source note | uspto-grants-1992_02 |