Formaldehyde → HCID 19910071, compound

Participants

Reaction Steps

3-Benzyl-3,8-diazabicyclo[4.3.0]non-1(6)-ene dihydrobromide (0.75 g) was refluxed in 85% formic acid (10 ml) and 37% formaline (7 ml) for 5 hours. The solvents were removed under reduced pressure and the solid was washed with isopropanol ethylether (2:1) to give 3-benzyl-8-methyl-3,8-diazabicyclo[4.3.0]non-1(6)-ene dihydrobromide (0.64 g, yield 82%).

Provenance & Evidence