Acetic Acid → HCID 19908383, compound

Participants

Reaction Steps

A mixture of 12.0 g of the compound 4c), 30 ml of glacial acetic acid and 70 ml of chloroform is heated under reflux for 3 h. After cooling to room temperature, it is washed with sodium bicarbonate solution and with water, and the chloroform solution is dried using sodium sulphate and concentrated. The residue is recrystallized from tert-butyl methyl ether.

Provenance & Evidence