HRID1534971

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6344

Dichloromethane

CH2Cl2

结构：C1=Cc2nc1c(-c1ccccc1)c1nc(c(-c3ccccc3)c3ccc([nH]3)c(-c3ccccc3)c3ccc([nH]3)c2-c2ccccc2)C=C1

HCID70186

未命名化合物

HCID165397

Cupric acetate monohydrate

C4H8CuO5

PRODUCTS

生成物

结构：C1=Cc2nc1c(-c1ccccc1)c1ccc([nH]1)c(-c1ccccc1)c1nc(c(-c3ccccc3)c3ccc([nH]3)c2-c2ccccc2)C=C1.[Cu+2]

HCID135741320

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

Tetraphenylporphyrin (II) (16.80 g., 27.3 mmol) is dissolved in 2000 ml of chloroform under reflux. Copper (II) acetate monohydrate (5.45 g., 27.3 mmol) is dissolved in 600 ml of methanol, and added dropwise to the methylene chloride solution in about 15 minutes. After the addition is over, the solution is refluxed for 30 minutes and cooled. The completion of the reaction is checked by UV-VIS spectrophotometry. The product IIa is isolated by evaporation of the solvents.

WORKUP

后处理

temperatureunder reflux
additionAfter the addition
temperatureis refluxed for 30 minutes
temperaturecooled
customThe product IIa is isolated by evaporation of the solvents

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e56dc25a2c0b4674950da31342da095e
来源数据集: uspto-grants-1992_02
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05091502
来源说明: uspto-grants-1992_02

反应 SMILES

[CH:1]1[CH:2]=[CH:3][C:4]([C:7]2[C:8]3[NH:12][C:11]([C:13]([C:43]4[CH:44]=[CH:45][CH:46]=[CH:47][CH:48]=4)=[C:14]4[CH:42]=[CH:41][C:16](=[C:17]([C:35]5[CH:36]=[CH:37][CH:38]=[CH:39][CH:40]=5)[C:18]5[CH:34]=[CH:33][C:20](=[C:21]([C:27]6[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=6)[C:22]6[CH:23]=[CH:24][C:25]=2[N:26]=6)[N:19]=5)[NH:15]4)=[CH:10][CH:9]=3)=[CH:5][CH:6]=1.O.C([O-])(=O)C.[Cu+2:54].C([O-])(=O)C.C(Cl)Cl>C(Cl)(Cl)Cl.CO>[C:43]1([C:13]2[C:11]3[NH:12][C:8](=[CH:9][CH:10]=3)[C:7]([C:4]3[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=3)=[C:25]3[N:26]=[C:22]([CH:23]=[CH:24]3)[C:21]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)=[C:20]3[NH:19][C:18]([CH:34]=[CH:33]3)=[C:17]([C:35]3[CH:36]=[CH:37][CH:38]=[CH:39][CH:40]=3)[C:16]3=[N:15][C:14]=2[CH:42]=[CH:41]3)[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1.[Cu+2:54]