Hydrochloric Acid → HCID 19070012, compound

HRID 1535004Notes

Reaction equation

HRID 1535004 reaction equation
[OH:1][C:2]1[CH:3]=[C:4](C(O)=O)[C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[CH:6][CH:7]=1.[OH-:17].[K+].[CH2:19](Br)[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32].Cl.[CH2:35]([OH:37])C>O>[CH2:19]([O:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[CH:10][C:11]([C:35]([OH:37])=[O:17])=[CH:12][CH:13]=2)=[CH:4][CH:3]=1)[CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32]

Participants

7

Reactant 5

HCID 313Hydrochloric AcidHCID 702EthanolHCID 8208Myristyl bromideHCID 14797Potassium HydroxideHCID 17997097HCID 17997097, compound

Product 1

HCID 19070012HCID 19070012, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2.14 g of p-hydroxybiphenylcarboxylic acid and 1.12 g of potassium hydroxide were dissolved in a mixture of 300 ml of ethanol and 40 ml of water. Then 3.02 ml of tetradecyl bromide was added thereto and the mixture was heated under reflux for 12 hours. Next, 13.5 ml of 2M hydrochloric acid was added to the reaction mixture and the crystals thus precipitated were filtered. Thus 2.20 g of 4'-n-tetradecyloxybiphenyl-4-carboxylic acid was obtained.

Workup

  1. temperaturethe mixture was heated
  2. temperatureunder reflux for 12 hours
  3. customthe crystals thus precipitated
  4. filtrationwere filtered

Sources & evidence

ORD record
ord-a4deb6eca42c4628b4547b98be758e54
Source dataset
uspto-grants-1992_02
Patent number
US05091557

Reaction notes

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