Thionyl Chloride → Benzene, (2-chloroethoxy)-

HRID 1535029Notes

Reaction equation

HRID 1535029 reaction equation
[O:1]([CH2:8][CH2:9]O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:13])=O>[Cl-].C([N+](C)(C)C)C1C=CC=CC=1.ClCCl>[O:1]([CH2:8][CH2:9][Cl:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 2

HCID 24386Thionyl ChlorideHCID 31236Phenoxyethanol

Product 1

HCID 12156Benzene, (2-chloroethoxy)-

Reagents, catalysts & solvents 2

HCID 5963Benzyltrimethylammonium chlorideCatalystHCID 6344DichloromethaneSolvent

Procedure

reacting 2-Phenoxy-ethanol with thionyl chloride in the presence of benzyl-trimethylammonium chloride in a molar ratio of 28:1 respectively, in dichloromethane as solvent, at a temperature of from about 0° C. to 50° C. to form 2-phenoxy-ethyl chloride;

Sources & evidence

ORD record
ord-dcfbef8107a44f7c914ac609c638c08b
Source dataset
uspto-grants-1992_02
Patent number
US05091577

Reaction notes

Loading…