Thionyl Chloride → Benzene, (2-chloroethoxy)-

HRID 1535030Notes

Reaction equation

HRID 1535030 reaction equation
[O:1]([CH2:8][CH2:9]O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:13])=O>[Cl-].C([N+](C)(C)C)C1C=CC=CC=1.ClCCl>[O:1]([CH2:8][CH2:9][Cl:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 2

HCID 24386Thionyl ChlorideHCID 31236Phenoxyethanol

Product 1

HCID 12156Benzene, (2-chloroethoxy)-

Reagents, catalysts & solvents 2

HCID 5963Benzyltrimethylammonium chlorideCatalystHCID 6344DichloromethaneSolvent

Procedure

reacting 2-phenoxyethanol with thionyl chloride in the presence of benzyl-trimethyl-ammonium chloride in a molar ratio of 28:1 respectively in dichloromethane as solvent, at a temperature of from about 0° C. to 50° C. to form 2-phenoxyethyl chloride;

Sources & evidence

ORD record
ord-49dc006ae7e4469bb336d7467f048c92
Source dataset
uspto-grants-1992_02
Patent number
US05091577

Reaction notes

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