Formaldehyde → Tert-butyl 4-({1-[2-(4-cyanophenyl)ethyl]-4-hydroxypiperidin-4-ylmethyl}methylamino)benzoate
Reaction equation
[BH4-:8].[C:10](#[N:11])[c:12]1[cH:13][cH:14][c:15]([CH2:18][CH2:19][N:20]2[CH2:21][CH2:22][C:23]([OH:26])([CH2:27][NH:28][c:29]3[cH:30][cH:31][c:32]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[cH:40][cH:41]3)[CH2:24][CH2:25]2)[cH:16][cH:17]1.[CH2:6]=[O:7].[Na+:42].[Na+:9].[O:47]1[CH2:48][CH2:49][CH2:50][CH2:51]1.[OH:43][C:44](=[O:45])[O-:46].[S:1](=[O:2])(=[O:3])([OH:4])[OH:5]>>[C:10](#[N:11])[c:12]1[cH:13][cH:14][c:15]([CH2:18][CH2:19][N:20]2[CH2:21][CH2:22][C:23]([OH:26])([CH2:27][N:28]([c:29]3[cH:30][cH:31][c:32]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[cH:40][cH:41]3)[CH3:44])[CH2:24][CH2:25]2)[cH:16][cH:17]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-72d130558a644a14b500e755384cdb91
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…