Tetrahydrofuran → N-butyl-4-[2-(4-fluorophenyl)-7-methylpyrazolo[1,5-a]pyridin-3-yl]-2-pyrimidinamine

HRID 1535130Notes

Reaction equation

HRID 1535130 reaction equation
[CH2:1]([CH2:2][CH2:3][CH3:4])[NH:5][c:6]1[n:7][cH:8][cH:9][c:10](-[c:12]2[c:13](-[c:22]3[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]3)[n:14][n:15]3[c:16]2[cH:17][cH:18][cH:19][c:20]3[Cl:21])[n:11]1.[CH3:29][Zn:30][CH3:31].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[NH:5][c:6]1[n:7][cH:8][cH:9][c:10](-[c:12]2[c:13](-[c:22]3[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]3)[n:14][n:15]3[c:16]2[cH:17][cH:18][cH:19][c:20]3[CH3:29])[n:11]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 22174847N-butyl-4-[7-chloro-2-(4-fluorophenyl)pyrazolo[1,5-a]pyridin-3-yl]-2-pyrimidinamineHCID 178477796HCID 178477796, compound

Product 1

HCID 10292858N-butyl-4-[2-(4-fluorophenyl)-7-methylpyrazolo[1,5-a]pyridin-3-yl]-2-pyrimidinamine

Sources & evidence

ORD record
ord-137019ad0ebc4eac90ac36b726a25e76
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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