Trimethylamine → 4-tert-Butyl-2-(1-Boc-piperidin-4-yloxy)benzyl Alcohol

HRID 1535272Notes

Reaction equation

HRID 1535272 reaction equation
[BH3:5].[C:6]([CH3:7])([CH3:8])([CH3:9])[c:10]1[cH:11][c:12]([O:19][CH:20]2[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]2)[c:13]([C:14](=[O:15])[OH:16])[cH:17][cH:18]1.[CH3:1][N:2]([CH3:3])[CH3:4].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[C:6]([CH3:7])([CH3:8])([CH3:9])[c:10]1[cH:11][c:12]([O:19][CH:20]2[CH2:21][CH2:22][N:23]([C:26](=[O:27])[O:28][C:29]([CH3:30])([CH3:31])[CH3:32])[CH2:24][CH2:25]2)[c:13]([CH2:14][OH:15])[cH:17][cH:18]1

Participants

5

Reactant 4

HCID 1146TrimethylamineHCID 6331BoraneHCID 8028TetrahydrofuranHCID 685305052-(N-Boc-piperidine-4-yloxy)-4-(tert-butyl)benzoic acid

Product 1

HCID 576024554-tert-Butyl-2-(1-Boc-piperidin-4-yloxy)benzyl Alcohol

Sources & evidence

ORD record
ord-4b29afe4ba9c443989e05592f4848bad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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