反应详情

A solution of 7-(hydroxymethyl)-2,3-dihydro-5(1H)-indolizinone (237 mg, 1.44 mmol) in acetone (12 ml) was treated with IBX (603 mg, 2.16 mmol) and heated at reflux for 1 h. The mixture was then evaporated, dissolved in dichloromethane and filtered, redissolved in dichloromethane and filtered again to provide the slightly impure desired product (238 mg, 101%)

1. temperatureheated
2. temperatureat reflux for 1 h
3. customThe mixture was then evaporated
4. dissolutiondissolved in dichloromethane
5. filtrationfiltered
6. dissolutionredissolved in dichloromethane
7. filtrationfiltered again