HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-(Hydroxymethyl)-2,3-dihydro-5(1H)-indolizinone → HCID 57486894, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-(Hydroxymethyl)-2,3-dihydro-5(1H)-indolizinone | HCID 57486893 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 57486894 | HCID 57486894 | 101.3% |
Reaction Steps
A solution of 7-(hydroxymethyl)-2,3-dihydro-5(1H)-indolizinone (237 mg, 1.44 mmol) in acetone (12 ml) was treated with IBX (603 mg, 2.16 mmol) and heated at reflux for 1 h. The mixture was then evaporated, dissolved in dichloromethane and filtered, redissolved in dichloromethane and filtered again to provide the slightly impure desired product (238 mg, 101%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07732461B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-5100170924614e678045d8c09e389bbb |
| Source note | uspto-grants-2010_06 |