Dichloromethane → (6-Bromo-imidazo[1,2-a]pyrazin-8-yl)-(1H-indol-6-yl)-amine

HRID 1535501Notes

Reaction equation

HRID 1535501 reaction equation
[C:1]([O:2][C:3](=[O:4])[n:8]1[cH:9][cH:10][c:11]2[cH:12][cH:13][c:14]([NH:17][c:18]3[c:19]4[n:20]([cH:21][c:22]([Br:24])[n:23]3)[cH:25][cH:26][n:27]4)[cH:15][c:16]12)([CH3:5])([CH3:6])[CH3:7].[Cl:35][CH2:36][Cl:37].[F:28][C:29]([F:30])([F:31])[C:32]([OH:33])=[O:34]>>[nH:8]1[cH:9][cH:10][c:11]2[cH:12][cH:13][c:14]([NH:17][c:18]3[c:19]4[n:20]([cH:21][c:22]([Br:24])[n:23]3)[cH:25][cH:26][n:27]4)[cH:15][c:16]12

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 865979236-(6-Bromo-imidazo[1,2-a]pyrazin-8-ylamino)-indole-1-carboxylic acid tert-butyl ester

Product 1

HCID 57447604(6-Bromo-imidazo[1,2-a]pyrazin-8-yl)-(1H-indol-6-yl)-amine

Sources & evidence

ORD record
ord-9feba73a216d4fa8b83f44711fdc5cff
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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