Hydrochloric Acid → 7-Bromo-5-(2-fluoro-phenyl)-3-methyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one

HRID 1535566Notes

Reaction equation

HRID 1535566 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]([CH3:9])[C:10]([NH:11][c:12]1[c:13]([C:19](=[O:5])[c:20]2[c:21]([F:26])[cH:22][cH:23][cH:24][cH:25]2)[cH:14][c:15]([Br:18])[cH:16][cH:17]1)=[O:28])([CH3:6])([CH3:27])[CH3:29].[Cl:31][CH:32]([Cl:33])[Cl:34].[ClH:30]>>[N:7]1=[C:19]([c:20]2[c:21]([F:26])[cH:22][cH:23][cH:24][cH:25]2)[c:13]2[c:12]([cH:17][cH:16][c:15]([Br:18])[cH:14]2)[NH:11][C:10](=[O:28])[CH:8]1[CH3:9]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 6212ChloroformHCID 68523676{1-[4-Bromo-2-(2-fluorobenzoyl)-phenylcarbamoyl]-ethyl)-carbamic acid tert-butyl ester

Product 1

HCID 685254147-Bromo-5-(2-fluoro-phenyl)-3-methyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one

Sources & evidence

ORD record
ord-ff9f67dbb2984ff3b1bd5a0af496da7b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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