Water → Ethyl 4-(4-benzylpiperazin-1-yl)benzoate

HRID 1535620Notes

Reaction equation

HRID 1535620 reaction equation
[CH3:26][N:27]([CH3:28])[C:29](=[O:30])[CH3:31].[F:14][c:15]1[cH:16][cH:17][c:18]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[cH:24][cH:25]1.[OH2:32].[c:1]1([CH2:7][N:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][N:8]2[CH2:9][CH2:10][N:11]([c:15]3[cH:16][cH:17][c:18]([C:19](=[O:20])[O:21][CH2:22][CH3:23])[cH:24][cH:25]3)[CH2:12][CH2:13]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 962WaterHCID 31374DimethylacetamideHCID 67976Benzoic acid, 4-fluoro-, ethyl esterHCID 759941-Benzylpiperazine

Product 1

HCID 14765277Ethyl 4-(4-benzylpiperazin-1-yl)benzoate

Sources & evidence

ORD record
ord-84490aa8a64949db8456ff7d5f8d94a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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